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Senescence-associated secretory phenotype (SASP)

A smiling young woman recovering from cancer treatment raises her arms in a victorious pose, symbolizing strength and resilience. The image captures a hopeful outlook for patients benefiting from new cancer therapies like dual PROTAC degraders, which not only fight tumors but may also promote healthy aging by targeting senescent cells.

New Cancer Drug Could Boost Longevity

New cancer therapy targets BCL-xL/BCL-2 to fight tumors and clear senescent cells—paving the way for safer, longer-lasting anti-aging treatments.

April 1, 2025

Biotechnology·Health·Products & Supplements·Science

A weary janitor kneels in a deteriorating, debris-filled room, meticulously polishing a small, perfectly clean patch of floor while cracked walls, leaking pipes, and scattered trash surround him, symbolizing obsessive focus amid widespread decay.

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

April 21, 2026

A 2026 Nature Aging paper identifies a distinct p21+TREM2+ senescent

Seragon Publishes Data on Longevity Drug SRN-901, Showing Record-Breaking Lifespan Extension in Mice

April 16, 2026

SRN-901 extends lifespan 33% and reduces frailty by 70%, reshaping

Visualization of genomic activation and cardiac aging showing LINE-1 increase over time and potential reversal through intervention, highlighting mechanisms of heart disease and longevity therapeutics

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

April 15, 2026

A Nature Aging study shows how LINE-1 retrotransposons trigger inflammation

Close-up scientific illustration of a mitochondrion with intact cristae structure, representing cellular energy production and its role in aging, mitochondrial dysfunction, and longevity biology.

A Death Protein That Doesn’t Kill: The Hidden Driver of Stem Cell Aging

April 13, 2026

A new study reveals how MLKL damages mitochondria in stem