A long-term dasatinib-and-quercetin study in aged mice used proteomics and singlecell sequencing to show senolytic kidney rejuvenation, restoring Klotho, PPARα metabolism, and repair.
A 2026 Nature Biomedical Engineering study shows how old human serum rapidly induces aging in organ-chip tissues, uncovering systemic drivers of aging and new
A Nature Aging study shows how LINE-1 retrotransposons trigger inflammation and cardiac aging through cGAS-STING signaling. Mechanisms, limits, and longevity implications.