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Autoimmune diseases

A doctor wearing a white coat and a surgical mask is holding a tablet and pointing at it. In the foreground, a digital hologram of a stomach, composed of a glowing blue wireframe, is superimposed. The image suggests the use of advanced medicine in gastroenterology or digestive health.

Key Cellular Guardians Can Turn Deadly: Perspective on NLRC5

NLRC5 drives inflammatory cell death in diseases like colitis. Targeting NAD+ or inhibiting NLRC5 could offer promising treatments, reducing inflammation.

October 23, 2024

Biotechnology·Health·Lifestyle·Science

A weary janitor kneels in a deteriorating, debris-filled room, meticulously polishing a small, perfectly clean patch of floor while cracked walls, leaking pipes, and scattered trash surround him, symbolizing obsessive focus amid widespread decay.

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

April 21, 2026

A 2026 Nature Aging paper identifies a distinct p21+TREM2+ senescent

Seragon Publishes Data on Longevity Drug SRN-901, Showing Record-Breaking Lifespan Extension in Mice

April 16, 2026

SRN-901 extends lifespan 33% and reduces frailty by 70%, reshaping

Visualization of genomic activation and cardiac aging showing LINE-1 increase over time and potential reversal through intervention, highlighting mechanisms of heart disease and longevity therapeutics

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

April 15, 2026

A Nature Aging study shows how LINE-1 retrotransposons trigger inflammation

Close-up scientific illustration of a mitochondrion with intact cristae structure, representing cellular energy production and its role in aging, mitochondrial dysfunction, and longevity biology.

A Death Protein That Doesn’t Kill: The Hidden Driver of Stem Cell Aging

April 13, 2026

A new study reveals how MLKL damages mitochondria in stem

Autoimmune diseases

Key Cellular Guardians Can Turn Deadly: Perspective on NLRC5

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Brandon Rodriguez

Emily Wilson

Christopher Martinez

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Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

A Death Protein That Doesn’t Kill: The Hidden Driver of Stem Cell Aging

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Autoimmune diseases

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