Geroscience

A researcher examines cultured cells through a microscope in a biomedical laboratory.

Autophagy and Senescent Cells: Restoring the Immune Cleanup

Restoring a cellular recycling pathway helped immune cells clear senescent cells in mice.

October 28, 2026

Biotechnology·Science·Technology

A woman in midlife sits beside a sunlit kitchen window, holding a mug and looking toward the garden.

Menopause and Aging: Study Maps a Sharp Physiological Transition

A large study reveals coordinated physiological changes around menopause, offering a clearer view of midlife aging.

October 23, 2026

Biotechnology·Health·Lifestyle·Science

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

Changing the lipid mix inside lysosomes reduced senescence in mouse kidney cells.

October 21, 2026

Biotechnology·Diet·Health·Science

SRSF1 and Aging: A Gene-Splicing Target Shows Promise in Mice

A gene-splicing protein reduced frailty progression in aged mice, offering a new target for aging research.

October 16, 2026

Biotechnology·Science

Blue wireframe figure raises a capsule to their mouth as a golden glow radiates from the kidney area, symbolizing senolytic rejuvenation.

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

A long-term dasatinib-and-quercetin study in aged mice used proteomics and singlecell sequencing to show senolytic kidney rejuvenation, restoring Klotho, PPARα metabolism, and repair.

July 17, 2026

Biotechnology·Health·Products & Supplements·Science

A photorealistic illustration of a lipid bilayer cell membrane undergoing oxidative damage, showing an intact, orderly membrane on the left transitioning into a disrupted region on the right where lipid chains are fragmented and breaking apart, with glowing orange-red oxidative reactions and nearby iron ions (Fe²⁺) catalyzing the damage.

Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

A new Cell Metabolism study reveals ferro-aging, linking iron, lipid peroxidation, and cellular senescence, with surprising primate data on vitamin C.

April 24, 2026

Biotechnology·Diet·Health·Products & Supplements·Science

A weary janitor kneels in a deteriorating, debris-filled room, meticulously polishing a small, perfectly clean patch of floor while cracked walls, leaking pipes, and scattered trash surround him, symbolizing obsessive focus amid widespread decay.

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

A 2026 Nature Aging paper identifies a distinct p21+TREM2+ senescent macrophage state driving liver disease and chronic inflammation, with implications for senolytics and longevity

April 21, 2026

Biotechnology

Visualization of genomic activation and cardiac aging showing LINE-1 increase over time and potential reversal through intervention, highlighting mechanisms of heart disease and longevity therapeutics

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

A Nature Aging study shows how LINE-1 retrotransposons trigger inflammation and cardiac aging through cGAS-STING signaling. Mechanisms, limits, and longevity implications.

April 15, 2026

Biotechnology·Science

Close-up scientific illustration of a mitochondrion with intact cristae structure, representing cellular energy production and its role in aging, mitochondrial dysfunction, and longevity biology.

A Death Protein That Doesn’t Kill: The Hidden Driver of Stem Cell Aging

A new study reveals how MLKL damages mitochondria in stem cells without killing them, offering a new lens on aging and longevity biology.

April 13, 2026

Biotechnology·Science

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

GrimAge and iAge track real world function across adulthood, linking biological age to VO2max and mobility, and clarifying how inflammation drives decline.

October 30, 2025

Biotechnology·Science·Technology

1 2 Next

Autophagy and Senescent Cells: Restoring the Immune Cleanup

Menopause and Aging: Study Maps a Sharp Physiological Transition

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

SRSF1 and Aging: A Gene-Splicing Target Shows Promise in Mice

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

A Death Protein That Doesn’t Kill: The Hidden Driver of Stem Cell Aging

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

Recent Posts

Recent Comments

Authors

Brandon Rodriguez

Emily Wilson

Christopher Martinez

Most Read

Autophagy and Senescent Cells: Restoring the Immune Cleanup

Menopause and Aging: Study Maps a Sharp Physiological Transition

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

Suggestions

Geroscience

Recent Posts

Recent Comments

Authors

Most Read