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vascular aging

A curated still life of polyphenol-rich foods arranged against a serene turquoise backdrop. A crisp red-striped apple rests in the foreground, while squares of dark chocolate perch on minimalist pale-blue blocks beside hazelnuts, loose green tea leaves, and a handwritten “Polyphenols” label. Behind them, clusters of green grapes, ruby strawberries, a glossy purple onion, and a single white garlic bulb create a vibrant tableau of color and texture, evoking the natural abundance of plant-based compounds that shape human health and longevity.

Polyphenols and Longevity, Reviewed!

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

December 1, 2025

Biotechnology·Diet·Health·Science·Technology

An image of a questionaire with a single question, asking "Progeria: Do you know about it? There are two boxes for "Yes" and "No" with a pen hovering over the "No" box.

Progeria, Progerin, and the Playbook of Human Aging

Learn about Progeria, what it is, why longevity researchers are interested, and how it impacts aging.

September 25, 2025

Biotechnology·Health·Science

The image shows a close-up of a person’s fingers gently holding a glowing point of light. Above the light, a three-dimensional DNA double helix made of tiny, reflective particles rises upward against a smooth, dark blue background. The scene gives the impression of someone delicately holding or creating genetic material, symbolizing concepts like biotechnology, synthetic biology.

Synthetic Biology vs. Aging in the Quest for Human Longevity

Synthetic biology is rewiring aging with gene circuits, senolytics, and reprogramming to boost healthspan while building in strict safety controls.

August 14, 2025

Biotechnology·Health·Science·Technology

A photorealistic illustration of a lipid bilayer cell membrane undergoing oxidative damage, showing an intact, orderly membrane on the left transitioning into a disrupted region on the right where lipid chains are fragmented and breaking apart, with glowing orange-red oxidative reactions and nearby iron ions (Fe²⁺) catalyzing the damage.

Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

April 24, 2026

A new Cell Metabolism study reveals ferro-aging, linking iron, lipid

Seragon Publishes Data on Longevity Drug SRN-901, Showing Record-Breaking Lifespan Extension in Mice

April 23, 2026

SRN-901 extends lifespan 33% and reduces frailty by 70%, reshaping

A weary janitor kneels in a deteriorating, debris-filled room, meticulously polishing a small, perfectly clean patch of floor while cracked walls, leaking pipes, and scattered trash surround him, symbolizing obsessive focus amid widespread decay.

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

April 21, 2026

A 2026 Nature Aging paper identifies a distinct p21+TREM2+ senescent

Visualization of genomic activation and cardiac aging showing LINE-1 increase over time and potential reversal through intervention, highlighting mechanisms of heart disease and longevity therapeutics

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

April 15, 2026

A Nature Aging study shows how LINE-1 retrotransposons trigger inflammation

vascular aging

Polyphenols and Longevity, Reviewed!

Progeria, Progerin, and the Playbook of Human Aging

Synthetic Biology vs. Aging in the Quest for Human Longevity

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Brandon Rodriguez

Emily Wilson

Christopher Martinez

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Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

LINE-1 and Cardiac Aging: When the Genome Stops Staying Quiet

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vascular aging

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