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Science

An older man sits on a comfortable living room sofa, gently focused as he practices an acoustic guitar, his posture relaxed but intent. Soft daylight fills the room, and the warm wood of the guitar contrasts with the quiet calm of the space. His expression shows both concentration and joy, capturing the beauty of learning something new later in life — the quiet, meaningful effort that keeps the mind alive and the spirit engaged.

What “Difficult Joy” Means (and why it matters for aging)

Discover how challenging, joyful learning strengthens the brain, builds resilience, and supports healthy aging through neuroplasticity and purposeful effort.

November 5, 2025

Health·Lifestyle·Science

A researcher wearing white medical gloves holds a single capsule filled with multicolored microbeads, suspended against a soft-focus background of intertwining DNA double helices. The image symbolizes the fusion of genetics and medicine—precision therapies tailored to the individual—highlighting the promise of pharmacogenomics in shaping personalized, age-responsive treatments.

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

How genes and biological age shape drug response, and how pharmacogenomics improves safety and effectiveness for older adults.

November 3, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

GrimAge and iAge track real world function across adulthood, linking biological age to VO2max and mobility, and clarifying how inflammation drives decline.

October 30, 2025

Biotechnology·Science·Technology

A woman sits cross-legged on a mountain ledge at sunrise, hands resting in quiet meditation. Below her, a sea of clouds drifts through shadowed valleys, while the horizon glows with golden light. The image captures a moment of stillness and balance, symbolizing alignment between body, mind, and the natural rhythm of the day.

Why “information timing” matters for longevity

Limiting late-night digital input may reduce stress, preserve circadian alignment, and slow aging—an attention diet for your longevity.

October 28, 2025

Diet·Health·Lifestyle·Science

An open spiral notebook rests on a wooden surface, its ruled page filled with the bold red word “Metformin,” underlined for emphasis. A stethoscope, partly visible at the bottom edge, frames the scene and connects the handwritten note to medicine and health. The contrast of red ink against the lined paper suggests urgency and importance, while the rustic grain of the desk background gives the composition a grounded, tactile quality.

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

Can metformin slow aging? Explore evidence from animals, humans, and primates on its impact on longevity, metabolism, and cognition.

October 24, 2025

Biotechnology·Health·Science·Technology

Two hands form a circle against a blurred green landscape, framing a translucent set of recycling arrows that symbolize renewal and continuous cycles of life. Subtle glowing hexagons with icons for health, sustainability, and science float across the foreground, blending natural imagery with futuristic design to evoke the concept of cellular recycling and longevity.

Autophagy Shapes Aging: The City That Cleans Itself

Autophagy is the cell’s cleanup crew—declining with age but targetable by fasting, exercise, and new therapies to extend healthspan.

October 22, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science·Technology

A gloved hand steadies a clear petri dish while a pipette delivers a single droplet of liquid into its center, capturing the precision and delicacy of laboratory stem cell research.

Stem Cells For Longevity: What The Data Actually Says In 2025

A quick map of the landscape “Stem cell injections” cover several very different things in humans: Below I break down where there is persuasive

October 16, 2025

Biotechnology·Health·Science·Technology

A contemplative older woman sits at her desk, laptop open, glasses in hand, as an hourglass steadily drains on the table before her—a quiet metaphor for time, aging, and the rhythms that govern life.

Chronotherapy, aging, and the body’s master timetable

Chronotherapy for healthy aging: how timing sleep, light, meals, and meds can help—what’s proven, what’s hype—using current human evidence.

October 14, 2025

Health·Lifestyle·Science·Technology

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Genomic Instability: When the Instruction Manual Frays

How DNA damage, telomeres, mtDNA, and immune sensing drive aging, and which levers may slow the cascade from genome errors to tissue decline.

October 8, 2025

Biotechnology·Health·Science

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

Lipofuscin is the cell’s stubborn waste. See how it drives aging through lysosomal failure, oxidative stress, and ferroptosis, and what science is doing about

October 6, 2025

Biotechnology·Products & Supplements·Science·Technology

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Science

What “Difficult Joy” Means (and why it matters for aging)

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

Autophagy Shapes Aging: The City That Cleans Itself

Stem Cells For Longevity: What The Data Actually Says In 2025

Chronotherapy, aging, and the body’s master timetable

Genomic Instability: When the Instruction Manual Frays

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Emily Wilson

Christopher Martinez

Brandon Rodriguez

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What “Difficult Joy” Means (and why it matters for aging)

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

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