Buck Institute Aging Research - Longevityreview

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Buck Institute Aging Research

Illustration of a glowing human cell surrounded by soft light and colorful gradients, symbolizing cellular health, autophagy, and processes related to aging and longevity

The Autophagy Awakening: How Recycling Unlocks Longevity

Discover how autophagy, including microautophagy and non-canonical pathways, can delay aging and promote healthier, longer lives.

December 19, 2024

Biotechnology·Science

SRN-901

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

May 7, 2025

In a May 7, 2024 press release, Seragon Biosciences announced

3D illustration of mitochondria inside neural tissue, highlighting the intricate inner membrane structure (cristae) and electron transport chains. This visualization symbolizes mitochondrial function in energy production and its decline with age, a core topic in the article on how mitochondrial dysfunction contributes to aging and age-related disease.

Longevity Reviewed! How to Optimize Your Aging Mitochondria

May 2, 2025

Mitochondria decline with age, but science shows we can restore

3D molecular illustration of an i-motif DNA structure, showcasing the unique intercalated four-stranded cytosine-rich formation distinct from the canonical double helix in the background. The i-motif, stabilized under acidic conditions, plays a dynamic role in gene regulation and adds complexity to genomic architecture, contributing to the accumulation of DNA damage with age.

New Structures for DNA Damage Discovered: Implications for Aging

April 30, 2025

How DNA damage, repair failure, and mutational buildup silently drive

Futuristic digital interface featuring a magnifying glass over a glowing fingerprint, symbolizing biometric analysis and identity. Surrounding the fingerprint are high-tech visual elements, including DNA strands, molecular structures, human anatomical figures, and data graphs. The image represents the integration of genetics, artificial intelligence, and multi-omics technologies in the search for biological clues to exceptional longevity, aligning with Matter Bio's groundbreaking collaboration to decode the genetic foundations of extended human healthspan.

Can the Secrets of exceptional Longevity be Revealed? Matter Bio and Academia to Find Out

April 25, 2025

Matter Bio launches a historic collaboration to decode the genetics