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deregulated nutrient sensing

An image of a fuel gauge with a cartoon person in the middle holding up a barbell with weights on it, signifying the fuel gauge of a person instead of a vehicle.

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

How the body’s fuel sensors—mTOR, IGF-1, AMPK, and sirtuins—shape aging, and what human studies say about nutrient sensing, diet, exercise, drugs, and biomarkers that

August 29, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Genomic Instability: When the Instruction Manual Frays

October 8, 2025

How DNA damage, telomeres, mtDNA, and immune sensing drive aging,

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

October 6, 2025

Lipofuscin is the cell’s stubborn waste. See how it drives

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Celebrating the International Day of Older Persons

October 1, 2025

Your practical guide to longevity and being celebrated one day.

An image of two skeletons shaking hands and conversing in front of a black background. Above their skeleton skulls, a spooky, haunting font with sharp lines and jagged edges reads "The Bones Are Talking... Is Your Lifespan Listening?"

The Bones Are Talking. Is Your Lifespan Listening?

October 1, 2025

Bones do more than support—they secrete hormones like osteocalcin and

deregulated nutrient sensing

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

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Genomic Instability: When the Instruction Manual Frays

Celebrating the International Day of Older Persons

The Bones Are Talking. Is Your Lifespan Listening?

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deregulated nutrient sensing

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