Inflammaging

A curated still life of polyphenol-rich foods arranged against a serene turquoise backdrop. A crisp red-striped apple rests in the foreground, while squares of dark chocolate perch on minimalist pale-blue blocks beside hazelnuts, loose green tea leaves, and a handwritten “Polyphenols” label. Behind them, clusters of green grapes, ruby strawberries, a glossy purple onion, and a single white garlic bulb create a vibrant tableau of color and texture, evoking the natural abundance of plant-based compounds that shape human health and longevity.

Polyphenols and Longevity, Reviewed!

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

December 1, 2025

Biotechnology·Diet·Health·Science·Technology

A bright red balloon ruptures midair, frozen in the instant its membrane gives way, sending a crystalline explosion of water outward against a clear blue sky. Droplets scatter in every direction like fractured glass, capturing the drama of a boundary pushed past its limit and the sudden release of what was once contained.

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

If cells had a “do not open” drawer, it would be the lysosome: a membrane-bound, acidified organelle loaded with hydrolases that digest spent proteins,

November 19, 2025

Biotechnology·Science

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

GrimAge and iAge track real world function across adulthood, linking biological age to VO2max and mobility, and clarifying how inflammation drives decline.

October 30, 2025

Biotechnology·Science·Technology

Two hands form a circle against a blurred green landscape, framing a translucent set of recycling arrows that symbolize renewal and continuous cycles of life. Subtle glowing hexagons with icons for health, sustainability, and science float across the foreground, blending natural imagery with futuristic design to evoke the concept of cellular recycling and longevity.

Autophagy Shapes Aging: The City That Cleans Itself

Autophagy is the cell’s cleanup crew—declining with age but targetable by fasting, exercise, and new therapies to extend healthspan.

October 22, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science·Technology

A gloved hand steadies a clear petri dish while a pipette delivers a single droplet of liquid into its center, capturing the precision and delicacy of laboratory stem cell research.

Stem Cells For Longevity: What The Data Actually Says In 2025

A quick map of the landscape “Stem cell injections” cover several very different things in humans: Below I break down where there is persuasive

October 16, 2025

Biotechnology·Health·Science·Technology

A contemplative older woman sits at her desk, laptop open, glasses in hand, as an hourglass steadily drains on the table before her—a quiet metaphor for time, aging, and the rhythms that govern life.

Chronotherapy, aging, and the body’s master timetable

Chronotherapy for healthy aging: how timing sleep, light, meals, and meds can help—what’s proven, what’s hype—using current human evidence.

October 14, 2025

Health·Lifestyle·Science·Technology

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Genomic Instability: When the Instruction Manual Frays

How DNA damage, telomeres, mtDNA, and immune sensing drive aging, and which levers may slow the cascade from genome errors to tissue decline.

October 8, 2025

Biotechnology·Health·Science

3D-rendered illustration of a human cell with a detailed cutaway view showing the nucleus, endoplasmic reticulum, and multiple mitochondria. One mitochondrion is magnified in an inset, glowing with bright particle effects to depict active energy production and signaling. The image represents mitochondrial function, cellular energy metabolism, and the role of mitochondria in aging and mitophagy, aligning with themes from the article on mitochondrial health and complex I modulation.

Mitophagy vs. Complex I Inhibitors: Which is Better?

Discover how mitophagy and Complex I inhibitors impact aging, inflammation, and tissue repair—and which path may best support healthy mitochondrial function.

July 21, 2025

Biotechnology·Health·Products & Supplements·Science