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mtDNA dysfunction

3D molecular illustration of an i-motif DNA structure, showcasing the unique intercalated four-stranded cytosine-rich formation distinct from the canonical double helix in the background. The i-motif, stabilized under acidic conditions, plays a dynamic role in gene regulation and adds complexity to genomic architecture, contributing to the accumulation of DNA damage with age.

New Structures for DNA Damage Discovered: Implications for Aging

How DNA damage, repair failure, and mutational buildup silently drive aging, disease, and cellular decline—down to the molecular level.

April 30, 2025

Biotechnology·Science·Technology

3D molecular illustration of an i-motif DNA structure, showcasing the unique intercalated four-stranded cytosine-rich formation distinct from the canonical double helix in the background. The i-motif, stabilized under acidic conditions, plays a dynamic role in gene regulation and adds complexity to genomic architecture, contributing to the accumulation of DNA damage with age.

New Structures for DNA Damage Discovered: Implications for Aging

April 30, 2025

How DNA damage, repair failure, and mutational buildup silently drive

Futuristic digital interface featuring a magnifying glass over a glowing fingerprint, symbolizing biometric analysis and identity. Surrounding the fingerprint are high-tech visual elements, including DNA strands, molecular structures, human anatomical figures, and data graphs. The image represents the integration of genetics, artificial intelligence, and multi-omics technologies in the search for biological clues to exceptional longevity, aligning with Matter Bio's groundbreaking collaboration to decode the genetic foundations of extended human healthspan.

Can the Secrets of exceptional Longevity be Revealed? Matter Bio and Academia to Find Out

April 25, 2025

Matter Bio launches a historic collaboration to decode the genetics

SRN-901

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

April 25, 2025

In a May 7, 2024 press release, Seragon Biosciences announced

Rapamycin Reviewed! Longevity in Every Organism Tested

April 18, 2025

rapamycin, a groundbreaking compound, is reshaping our understanding of aging