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NAD+ metabolism

Young woman standing peacefully among blooming white lilac flowers in springtime, symbolizing seasonal renewal, natural rejuvenation, and longevity-enhancing environmental exposure.

Spring Time Unlocks Longevity Pathways

Spring time activates immune, circadian, and genetic pathways that enhance healthspan and promote longevity. Seasonal longevity science is a thing, and it could inform

March 19, 2025

Health·Lifestyle·Science

A doctor wearing a white coat and a surgical mask is holding a tablet and pointing at it. In the foreground, a digital hologram of a stomach, composed of a glowing blue wireframe, is superimposed. The image suggests the use of advanced medicine in gastroenterology or digestive health.

Key Cellular Guardians Can Turn Deadly: Perspective on NLRC5

NLRC5 drives inflammatory cell death in diseases like colitis. Targeting NAD+ or inhibiting NLRC5 could offer promising treatments, reducing inflammation.

October 23, 2024

Biotechnology·Health·Lifestyle·Science

A collection of white and blue capsules arranged on a white background, with some blue capsules forming the letters "AI." The image represents the intersection of artificial intelligence and drug discovery, reflecting advancements in AI-driven pharmaceutical research, including the development of senomorphic therapeutics like TNIK inhibitors.

New Senomorphic Strategy for Age-Related Diseases: TNIK Inhibition

March 28, 2025

TNIK inhibition with INS018_055 modulates senescence, reduces inflammation, and advances

Abstract blue line art illustration of diverse gut microbiota, including rod-shaped, spherical, and spiral bacterial forms, representing the complexity and richness of the human gut microbiome. This visual metaphorically conveys the microbiome's integral role in regulating aging, cognition, immunity, and overall longevity.

Microbiome and Longevity Reviewed! Insights from Long-Lived Humans

March 26, 2025

A New Kind of Organ In the landscape of human

A surreal Martian-like desert landscape under a star-filled sky, with a vibrant Milky Way galaxy stretching across the horizon. A shooting star streaks across the deep twilight gradient, blending from blue to pink to orange. Rugged red rock formations and scattered desert vegetation dot the barren terrain, evoking themes of space colonization, cognitive evolution, and the search for intelligent life beyond Earth. Ideal visual for the “Cognitive Ark” and longevity science in the Dumbpocalypse survival guide.

The Longevity Field Guide to Surviving the Dumbpocalypse

March 20, 2025

Earth IQs are crashing, but Mars is rising. Escape the

SRN-901

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

March 20, 2025

In a May 7, 2024 press release, Seragon Biosciences announced