senolytics

Seragon Publishes Data on Longevity Drug SRN-901, Showing Record-Breaking Lifespan Extension in Mice

SRN-901 extends lifespan 33% and reduces frailty by 70%, reshaping aging biology through coordinated, multi-pathway intervention.

October 21, 2026

Biotechnology·Health·Products & Supplements·Science·Technology

Blue wireframe figure raises a capsule to their mouth as a golden glow radiates from the kidney area, symbolizing senolytic rejuvenation.

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

A long-term dasatinib-and-quercetin study in aged mice used proteomics and singlecell sequencing to show senolytic kidney rejuvenation, restoring Klotho, PPARα metabolism, and repair.

July 17, 2026

Biotechnology·Health·Products & Supplements·Science

High-resolution scientific illustration of a central cluster of human cells exposed to two contrasting systemic environments. The left side shows a calm, blue, low-noise signaling field with sparse particles, where the cells appear uniform and stable. The right side shows a denser, warm-toned red/orange signaling field with more complex, dynamic particles, where the same cells appear slightly irregular and stressed. The image emphasizes how systemic signaling environments can influence cellular state without visible tissue damage.

Old Blood, Fast Aging: How a Human Organ-Chip Reveals the Biology of Systemic Aging

A 2026 Nature Biomedical Engineering study shows how old human serum rapidly induces aging in organ-chip tissues, uncovering systemic drivers of aging and new

April 29, 2026

Biotechnology·Science·Technology

A weary janitor kneels in a deteriorating, debris-filled room, meticulously polishing a small, perfectly clean patch of floor while cracked walls, leaking pipes, and scattered trash surround him, symbolizing obsessive focus amid widespread decay.

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

A 2026 Nature Aging paper identifies a distinct p21+TREM2+ senescent macrophage state driving liver disease and chronic inflammation, with implications for senolytics and longevity

April 21, 2026

Biotechnology

A side-by-side scene showing hands typing on a modern laptop on the left and hands using a vintage typewriter on the right, set against a warm, glowing yellow background, symbolizing the contrast between old and new approaches.

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Longevity science is shifting from NAD+ supplements to precision anti-aging therapies. Here’s what the data actually shows and what comes next.

March 21, 2026

Biotechnology·Diet·Science·Technology

A bright red balloon ruptures midair, frozen in the instant its membrane gives way, sending a crystalline explosion of water outward against a clear blue sky. Droplets scatter in every direction like fractured glass, capturing the drama of a boundary pushed past its limit and the sudden release of what was once contained.

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

If cells had a “do not open” drawer, it would be the lysosome: a membrane-bound, acidified organelle loaded with hydrolases that digest spent proteins,

November 19, 2025

Biotechnology·Science

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

Lipofuscin is the cell’s stubborn waste. See how it drives aging through lysosomal failure, oxidative stress, and ferroptosis, and what science is doing about

October 6, 2025

Biotechnology·Products & Supplements·Science·Technology

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Celebrating the International Day of Older Persons

Your practical guide to longevity and being celebrated one day.

October 1, 2025

Biotechnology·Diet·Health·Lifestyle·Politics·Science

The image shows a close-up of a person’s fingers gently holding a glowing point of light. Above the light, a three-dimensional DNA double helix made of tiny, reflective particles rises upward against a smooth, dark blue background. The scene gives the impression of someone delicately holding or creating genetic material, symbolizing concepts like biotechnology, synthetic biology.

Synthetic Biology vs. Aging in the Quest for Human Longevity

Synthetic biology is rewiring aging with gene circuits, senolytics, and reprogramming to boost healthspan while building in strict safety controls.

August 14, 2025

Biotechnology·Health·Science·Technology

3D-rendered illustration of a human cell with a detailed cutaway view showing the nucleus, endoplasmic reticulum, and multiple mitochondria. One mitochondrion is magnified in an inset, glowing with bright particle effects to depict active energy production and signaling. The image represents mitochondrial function, cellular energy metabolism, and the role of mitochondria in aging and mitophagy, aligning with themes from the article on mitochondrial health and complex I modulation.

Mitophagy vs. Complex I Inhibitors: Which is Better?

Discover how mitophagy and Complex I inhibitors impact aging, inflammation, and tissue repair—and which path may best support healthy mitochondrial function.

July 21, 2025

Biotechnology·Health·Products & Supplements·Science

1 2 Next

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

Old Blood, Fast Aging: How a Human Organ-Chip Reveals the Biology of Systemic Aging

Senescent Macrophages Aren’t What We Thought: A New Cell State Rewires Inflammaging

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

Celebrating the International Day of Older Persons

Synthetic Biology vs. Aging in the Quest for Human Longevity

Mitophagy vs. Complex I Inhibitors: Which is Better?

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