somatic mutation - Longevityreview

Your news source for longevity topics reviewed!

somatic mutation

3D molecular illustration of an i-motif DNA structure, showcasing the unique intercalated four-stranded cytosine-rich formation distinct from the canonical double helix in the background. The i-motif, stabilized under acidic conditions, plays a dynamic role in gene regulation and adds complexity to genomic architecture, contributing to the accumulation of DNA damage with age.

New Structures for DNA Damage Discovered: Implications for Aging

How DNA damage, repair failure, and mutational buildup silently drive aging, disease, and cellular decline—down to the molecular level.

April 30, 2025

Biotechnology·Science·Technology

A digital illustration of an x-shaped chromosome in the foreground with a nucleus in the background containing additional chromosomes. Chromosomes are in blue, with a visible telomere on each end-cap in gold, and centromeres glowing in pink.

The Countdown Inside Our Cells: Telomere Attrition Reviewed!

July 9, 2025

Telomere attrition—gradual loss of chromosome caps—links to heart disease, immune

An Ancient Gene Switch Could Unlock Unlimited Regeneration

July 3, 2025

Scientists restored tissue regeneration in mice by flipping an ancient

SRN-901

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

July 3, 2025

In a May 7, 2024 press release, Seragon Biosciences announced

An image of a doctor holding a holograph-generating tablet. The holograph displayed is a human next, with multiple boxes containing characteristics of aging surrounding it, representing the biomarkers of aging.

Biomarkers of Aging, Reviewed!

June 2, 2025

What two major 2025 studies reveal about the future of