Longevityreview

A sunlit forest path framed by lush green trees, but the center of the scene fades into a hazy, dark blur—evoking the experience of age-related macular degeneration, where the world remains vibrant at the edges while the heart of the view quietly disappears.

Aging’s Canary in The Coal Mine: Age-Related Macular Degeneration

AMD (age-related macular degeneration) reveals how the aging retina fails, from mitochondria to complement, with GA and wet forms. See what genetics, diet, and new drugs mean for vision.

November 11, 2025

Biotechnology·Health·Products & Supplements·Science

An older man sits on a comfortable living room sofa, gently focused as he practices an acoustic guitar, his posture relaxed but intent. Soft daylight fills the room, and the warm wood of the guitar contrasts with the quiet calm of the space. His expression shows both concentration and joy, capturing the beauty of learning something new later in life — the quiet, meaningful effort that keeps the mind alive and the spirit engaged.

What “Difficult Joy” Means (and why it matters for aging)

November 5, 2025

Health·Lifestyle·Science

A researcher wearing white medical gloves holds a single capsule filled with multicolored microbeads, suspended against a soft-focus background of intertwining DNA double helices. The image symbolizes the fusion of genetics and medicine—precision therapies tailored to the individual—highlighting the promise of pharmacogenomics in shaping personalized, age-responsive treatments.

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

November 3, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

Christopher Martinez

A woman sits cross-legged on a mountain ledge at sunrise, hands resting in quiet meditation. Below her, a sea of clouds drifts through shadowed valleys, while the horizon glows with golden light. The image captures a moment of stillness and balance, symbolizing alignment between body, mind, and the natural rhythm of the day.

Why “information timing” matters for longevity

Brandon Rodriguez

An open spiral notebook rests on a wooden surface, its ruled page filled with the bold red word “Metformin,” underlined for emphasis. A stethoscope, partly visible at the bottom edge, frames the scene and connects the handwritten note to medicine and health. The contrast of red ink against the lined paper suggests urgency and importance, while the rustic grain of the desk background gives the composition a grounded, tactile quality.

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

Tyler Kim

Diet

Diet·Health·Lifestyle·Science

Why “information timing” matters for longevity

October 28, 2025

Limiting late-night digital input may reduce stress, preserve circadian alignment, and slow aging—an attention diet for your longevity.

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Biotechnology·Diet·Health·Lifestyle·Politics·Science

Celebrating the International Day of Older Persons

October 1, 2025

Your practical guide to longevity and being celebrated one day.

Diet·Health

A Deep Dive into Dietary Fiber and Disease Prevention

September 18, 2025

Dietary fiber helps prevent chronic diseases like heart disease, type 2 diabetes, and chronic kidney disease. Increase fiber with whole grains, fruits, and vegetables.

Diet·Health·Lifestyle

Beyond the Hype: Understanding the Science of the Ketogenic Diet

September 16, 2025

The ketogenic diet promotes weight loss and better focus through low-carb, high-fat eating. Transition can be tough; consult a doctor before starting.

Latest

Biotechnology·Health·Products & Supplements·Science

Aging’s Canary in The Coal Mine: Age-Related Macular Degeneration

November 11, 2025

AMD (age-related macular degeneration) reveals how the aging retina fails, from mitochondria to complement, with GA and wet forms. See what genetics, diet, and

Health·Lifestyle·Science

What “Difficult Joy” Means (and why it matters for aging)

November 5, 2025

Discover how challenging, joyful learning strengthens the brain, builds resilience, and supports healthy aging through neuroplasticity and purposeful effort.

Biotechnology·Health·Lifestyle·Products & Supplements·Science

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

November 3, 2025

How genes and biological age shape drug response, and how pharmacogenomics improves safety and effectiveness for older adults.

Biotechnology·Science·Technology

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

October 30, 2025

GrimAge and iAge track real world function across adulthood, linking biological age to VO2max and mobility, and clarifying how inflammation drives decline.

Diet·Health·Lifestyle·Science

Why “information timing” matters for longevity

October 28, 2025

Limiting late-night digital input may reduce stress, preserve circadian alignment, and slow aging—an attention diet for your longevity.

Biotechnology·Health·Science·Technology

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

October 24, 2025

Can metformin slow aging? Explore evidence from animals, humans, and primates on its impact on longevity, metabolism, and cognition.

Two hands form a circle against a blurred green landscape, framing a translucent set of recycling arrows that symbolize renewal and continuous cycles of life. Subtle glowing hexagons with icons for health, sustainability, and science float across the foreground, blending natural imagery with futuristic design to evoke the concept of cellular recycling and longevity.

Biotechnology·Health·Lifestyle·Products & Supplements·Science·Technology

Autophagy Shapes Aging: The City That Cleans Itself

October 22, 2025

Autophagy is the cell’s cleanup crew—declining with age but targetable by fasting, exercise, and new therapies to extend healthspan.

A gloved hand steadies a clear petri dish while a pipette delivers a single droplet of liquid into its center, capturing the precision and delicacy of laboratory stem cell research.

Biotechnology·Health·Science·Technology

Stem Cells For Longevity: What The Data Actually Says In 2025

October 16, 2025

A quick map of the landscape “Stem cell injections” cover several very different things in humans: Below I break down where there is persuasive

A contemplative older woman sits at her desk, laptop open, glasses in hand, as an hourglass steadily drains on the table before her—a quiet metaphor for time, aging, and the rhythms that govern life.

Health·Lifestyle·Science·Technology

Chronotherapy, aging, and the body’s master timetable

October 14, 2025

Chronotherapy for healthy aging: how timing sleep, light, meals, and meds can help—what’s proven, what’s hype—using current human evidence.

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Biotechnology·Health·Science

Genomic Instability: When the Instruction Manual Frays

October 8, 2025

How DNA damage, telomeres, mtDNA, and immune sensing drive aging, and which levers may slow the cascade from genome errors to tissue decline.

1 2 3 … 19 Next

What “Difficult Joy” Means (and why it matters for aging)

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

Diet

Celebrating the International Day of Older Persons

A Deep Dive into Dietary Fiber and Disease Prevention

Beyond the Hype: Understanding the Science of the Ketogenic Diet

Latest

What “Difficult Joy” Means (and why it matters for aging)

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

Metformin and the Long Game: what a 60-year-old diabetes drug can teach us about slowing aging

Autophagy Shapes Aging: The City That Cleans Itself

Stem Cells For Longevity: What The Data Actually Says In 2025

Chronotherapy, aging, and the body’s master timetable

Genomic Instability: When the Instruction Manual Frays

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Emily Wilson

Christopher Martinez

Brandon Rodriguez

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What “Difficult Joy” Means (and why it matters for aging)

Longer, Better Lives through Pharmacogenomics: How Your Genes, Age, and Medicines Interact

Biological Age Clocks are Maturing, But Can They Actually Tell Us Who Will Stay Strong?

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