Caloric Restriction

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

Lipofuscin is the cell’s stubborn waste. See how it drives aging through lysosomal failure, oxidative stress, and ferroptosis, and what science is doing about

October 6, 2025

Biotechnology·Products & Supplements·Science·Technology

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Celebrating the International Day of Older Persons

Your practical guide to longevity and being celebrated one day.

October 1, 2025

Biotechnology·Diet·Health·Lifestyle·Politics·Science

An image of a fuel gauge with a cartoon person in the middle holding up a barbell with weights on it, signifying the fuel gauge of a person instead of a vehicle.

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

How the body’s fuel sensors—mTOR, IGF-1, AMPK, and sirtuins—shape aging, and what human studies say about nutrient sensing, diet, exercise, drugs, and biomarkers that

August 29, 2025

Biotechnology·Health·Lifestyle·Products & Supplements·Science

A futuristic image inside of a space station bedroom overlooking earth through a central window.

Are Anti-Aging Drugs Here?

Longevity drugs are real—and they target aging at its roots. Here’s why they matter, and how science is making long, healthy life possible for

May 30, 2025

Biotechnology·Products & Supplements·Science·Technology

Close-up of hands typing on a keyboard with a digital overlay of health-related icons like DNA, a heart, and a brain, representing the role of DNA methylation research in decoding and potentially reversing the aging process.

Cracking the Code of Aging: DNA Methylation Reviewed

Exploring how DNA methylation influences aging and the potential of lifestyle changes to reverse biological age.

February 3, 2025

Biotechnology·Diet·Health·Lifestyle·Products & Supplements·Science

An amber-colored bottle of dietary supplements spills white capsules and golden softgels onto a light orange surface, with a green measuring tape draped around it. The image evokes themes of health, wellness, and weight management, symbolizing the scientific pursuit of mimicking caloric restriction through supplements to promote longevity and vitality.

Secrets of Caloric Restriction Mimetics: A Path To Longevity

Caloric restriction mimetics offer the benefits of calorie reduction without extreme diets, targeting pathways linked to aging for a longer, healthier life.

October 31, 2024

Biotechnology·Diet·Health·Lifestyle·Science

Ora Biomedical Aims to Accelerate Longevity Intervention Research with the Million Molecule Challenge

Mitchell Lee, CEO of Ora Biomedical, is revolutionizing longevity research with high-throughput screening in C. elegans, aiming to screen over 1 million compounds in

November 27, 2023

Biotechnology·Science·Technology

Celebrating the International Day of Older Persons

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

Are Anti-Aging Drugs Here?

Cracking the Code of Aging: DNA Methylation Reviewed

Secrets of Caloric Restriction Mimetics: A Path To Longevity

Ora Biomedical Aims to Accelerate Longevity Intervention Research with the Million Molecule Challenge

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