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Cellular Senescence

A bright red balloon ruptures midair, frozen in the instant its membrane gives way, sending a crystalline explosion of water outward against a clear blue sky. Droplets scatter in every direction like fractured glass, capturing the drama of a boundary pushed past its limit and the sudden release of what was once contained.

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

If cells had a “do not open” drawer, it would be the lysosome: a membrane-bound, acidified organelle loaded with hydrolases that digest spent proteins,

November 19, 2025

Biotechnology·Science

A sunlit forest path framed by lush green trees, but the center of the scene fades into a hazy, dark blur—evoking the experience of age-related macular degeneration, where the world remains vibrant at the edges while the heart of the view quietly disappears.

Aging’s Canary in The Coal Mine: Age-Related Macular Degeneration

AMD (age-related macular degeneration) reveals how the aging retina fails, from mitochondria to complement, with GA and wet forms. See what genetics, diet, and

November 11, 2025

Biotechnology·Health·Products & Supplements·Science

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Genomic Instability: When the Instruction Manual Frays

How DNA damage, telomeres, mtDNA, and immune sensing drive aging, and which levers may slow the cascade from genome errors to tissue decline.

October 8, 2025

Biotechnology·Health·Science

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

Lipofuscin is the cell’s stubborn waste. See how it drives aging through lysosomal failure, oxidative stress, and ferroptosis, and what science is doing about

October 6, 2025

Biotechnology·Products & Supplements·Science·Technology

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Celebrating the International Day of Older Persons

Your practical guide to longevity and being celebrated one day.

October 1, 2025

Biotechnology·Diet·Health·Lifestyle·Politics·Science

The image shows a close-up of a person’s fingers gently holding a glowing point of light. Above the light, a three-dimensional DNA double helix made of tiny, reflective particles rises upward against a smooth, dark blue background. The scene gives the impression of someone delicately holding or creating genetic material, symbolizing concepts like biotechnology, synthetic biology.

Synthetic Biology vs. Aging in the Quest for Human Longevity

Synthetic biology is rewiring aging with gene circuits, senolytics, and reprogramming to boost healthspan while building in strict safety controls.

August 14, 2025

Biotechnology·Health·Science·Technology

3D rendering of NMN-loaded extracellular vesicles (sEVs) interacting with a cell surface, representing the advanced anti-aging therapy discussed in the article.

NAD+ & SIRT3 Power: New NMN-EVs Reverse Skin Aging in Mice

Revolutionary NMN-packed stem cell vesicles (NMN-sEVs) show stunning results in reversing skin aging in mice by boosting NAD+ and cellular repair.

July 18, 2025

Biotechnology·Science·Technology

A fit woman wearing high-waisted jeans and a crop top stands in a modern kitchen, partially putting on a white button-down shirt. Her toned midsection is visible, symbolizing the weight loss and metabolic health benefits often associated with Ozempic (semaglutide) as discussed in the context of anti-aging and longevity therapies.

Ozempic: The Unexpected Ally in the Quest for Longevity

Ozempic already treats more than diabetes—but it could redefine aging by targeting inflammation and metabolism itself.

April 4, 2025

Biotechnology·Diet·Health·Lifestyle·Politics·Products & Supplements·Science·Technology

A smiling young woman recovering from cancer treatment raises her arms in a victorious pose, symbolizing strength and resilience. The image captures a hopeful outlook for patients benefiting from new cancer therapies like dual PROTAC degraders, which not only fight tumors but may also promote healthy aging by targeting senescent cells.

New Cancer Drug Could Boost Longevity

New cancer therapy targets BCL-xL/BCL-2 to fight tumors and clear senescent cells—paving the way for safer, longer-lasting anti-aging treatments.

April 1, 2025

Biotechnology·Health·Products & Supplements·Science

A collection of white and blue capsules arranged on a white background, with some blue capsules forming the letters "AI." The image represents the intersection of artificial intelligence and drug discovery, reflecting advancements in AI-driven pharmaceutical research, including the development of senomorphic therapeutics like TNIK inhibitors.

New Senomorphic Strategy for Age-Related Diseases: TNIK Inhibition

TNIK inhibition with INS018_055 modulates senescence, reduces inflammation, and advances AI-driven longevity therapeutics.

March 28, 2025

Biotechnology·Science·Technology