If cells had a “do not open” drawer, it would be the lysosome: a membrane-bound, acidified organelle loaded with hydrolases that digest spent proteins,
AMD (age-related macular degeneration) reveals how the aging retina fails, from mitochondria to complement, with GA and wet forms. See what genetics, diet, and
GrimAge and iAge track real world function across adulthood, linking biological age to VO2max and mobility, and clarifying how inflammation drives decline.
Lipofuscin is the cell’s stubborn waste. See how it drives aging through lysosomal failure, oxidative stress, and ferroptosis, and what science is doing about