Longevityreview

A researcher examines cultured cells through a microscope in a biomedical laboratory.

Autophagy and Senescent Cells: Restoring the Immune Cleanup

Restoring a cellular recycling pathway helped immune cells clear senescent cells in mice.

October 28, 2026

Biotechnology·Science·Technology

A woman in midlife sits beside a sunlit kitchen window, holding a mug and looking toward the garden.

Menopause and Aging: Study Maps a Sharp Physiological Transition

October 23, 2026

Biotechnology·Health·Lifestyle·Science

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

October 21, 2026

Biotechnology·Diet·Health·Science

Seragon Publishes Data on Longevity Drug SRN-901, Showing Record-Breaking Lifespan Extension in Mice

Michael Lopez

SRSF1 and Aging: A Gene-Splicing Target Shows Promise in Mice

Brandon Rodriguez

Blue wireframe figure raises a capsule to their mouth as a golden glow radiates from the kidney area, symbolizing senolytic rejuvenation.

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

Tyler Kim

Diet

Biotechnology·Diet·Health·Science

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

October 21, 2026

Changing the lipid mix inside lysosomes reduced senescence in mouse kidney cells.

A photorealistic illustration of a lipid bilayer cell membrane undergoing oxidative damage, showing an intact, orderly membrane on the left transitioning into a disrupted region on the right where lipid chains are fragmented and breaking apart, with glowing orange-red oxidative reactions and nearby iron ions (Fe²⁺) catalyzing the damage.

Biotechnology·Diet·Health·Products & Supplements·Science

Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

April 24, 2026

A new Cell Metabolism study reveals ferro-aging, linking iron, lipid peroxidation, and cellular senescence, with surprising primate data on vitamin C.

A side-by-side scene showing hands typing on a modern laptop on the left and hands using a vintage typewriter on the right, set against a warm, glowing yellow background, symbolizing the contrast between old and new approaches.

Biotechnology·Diet·Science·Technology

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

March 21, 2026

Longevity science is shifting from NAD+ supplements to precision anti-aging therapies. Here’s what the data actually shows and what comes next.

A curated still life of polyphenol-rich foods arranged against a serene turquoise backdrop. A crisp red-striped apple rests in the foreground, while squares of dark chocolate perch on minimalist pale-blue blocks beside hazelnuts, loose green tea leaves, and a handwritten “Polyphenols” label. Behind them, clusters of green grapes, ruby strawberries, a glossy purple onion, and a single white garlic bulb create a vibrant tableau of color and texture, evoking the natural abundance of plant-based compounds that shape human health and longevity.

Biotechnology·Diet·Health·Science·Technology

Polyphenols and Longevity, Reviewed!

December 1, 2025

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

Latest

Diet

Omega Fatty Acids: 3, 6, and 9 Explained

September 2, 2025

What are Omega Fatty Acids? Omega-3, -6, and -9 fatty acids are all important dietary fats that play crucial roles in the human body.

An image of a fuel gauge with a cartoon person in the middle holding up a barbell with weights on it, signifying the fuel gauge of a person instead of a vehicle.

Biotechnology·Health·Lifestyle·Products & Supplements·Science

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

August 29, 2025

How the body’s fuel sensors—mTOR, IGF-1, AMPK, and sirtuins—shape aging, and what human studies say about nutrient sensing, diet, exercise, drugs, and biomarkers that

A young man in a black and red jacket sits on a grassy hillside at sunset, gently holding the face of a golden Labrador retriever. The two face each other closely, sharing an intimate and peaceful moment, with the blurred city skyline and vivid orange-pink sky glowing in the background. The dog’s mouth is slightly open as if panting or smiling, while the man looks at him with affection, creating a scene of companionship and tranquility.

Health·Lifestyle·Science

Do Dogs Help Us Age Better? Here’s What the Latest Science Actually Says.

August 26, 2025

Dog ownership can boost health and longevity—but also carries risks. Here’s what the latest science says about aging with canine companions.

A young woman staring at her phone in the dark while laying on her side in bed. A harsh blue light is emitting from her phone, while a softer blue light is being emitted on the back wall behind her bed.

Health·Lifestyle·Science

Blue light, sleep, and aging: what the strongest science actually says

August 19, 2025

Blue light shapes sleep and aging biology. Get bright days, dim evenings, and dark nights to protect melatonin, metabolism, and long term health.

The image shows a close-up of a person’s fingers gently holding a glowing point of light. Above the light, a three-dimensional DNA double helix made of tiny, reflective particles rises upward against a smooth, dark blue background. The scene gives the impression of someone delicately holding or creating genetic material, symbolizing concepts like biotechnology, synthetic biology.

Biotechnology·Health·Science·Technology

Synthetic Biology vs. Aging in the Quest for Human Longevity

August 14, 2025

Synthetic biology is rewiring aging with gene circuits, senolytics, and reprogramming to boost healthspan while building in strict safety controls.

A young woman asleep in her bed, covered by a fluffy white comforter and soft white pillows. A soft purple hue lights the image with an overlay of the word "Melatonin" and the melatonin chemical structure.

Biotechnology·Health·Lifestyle·Science

Circadian Rhythms and Longevity: The Science of Aging on Time

August 12, 2025

How circadian rhythms influence human aging—from metabolism and sleep to menopause, TRE, rapamycin, mitochondria and molecular clocks.

A microscope's view of the bone's trabacular structures, artificially colored in teal and red accents.

Biotechnology·Health·Science

Bone Deep: How Your Skeleton Secretly Shapes Your Longevity

August 8, 2025

Your skeleton does more than support you—it may regulate aging. Discover how bone hormones like osteocalcin shape metabolism, memory, and lifespan.

A cartoon image of a man in a blue suit jacket, yellow tie, and navy pants with his tie flapping in the wind to his right, set on the backdrop of a blue sky with fluffy white clouds. His right arm is bent at the elbow upwards as if to raise something above his head. Hovering above his open hand is a sparkling clock, symbolizing time management. His left are is also bent upward at the elbow and his hand is making the motion of spinning a basketball with an outstretched finder. Hovering above his finger is a pie chart with a light bulb inside illustrating the idea of proper structured procrastination can be achieved while improving time management and efficiency.

Health·Lifestyle·Science

What Is Structured Procrastination?

August 7, 2025

Structured procrastination may influence aging. Discover how motivation, stress, and health habits shape your lifespan—and what science says about delaying wisely.

An image of a syringe targeting a cancer cell on an orange background. Two cancer cells are in the background about to be targeted by the new immunotherapy.

Biotechnology·Science·Technology

Senolytic Immune Cells Get a Facelift

August 5, 2025

Explore how senolytic CAR-T and CAR-NK therapies are reshaping aging by clearing senescent cells and restoring youthful function.

3D-rendered illustration of a human cell with a detailed cutaway view showing the nucleus, endoplasmic reticulum, and multiple mitochondria. One mitochondrion is magnified in an inset, glowing with bright particle effects to depict active energy production and signaling. The image represents mitochondrial function, cellular energy metabolism, and the role of mitochondria in aging and mitophagy, aligning with themes from the article on mitochondrial health and complex I modulation.

Biotechnology·Health·Products & Supplements·Science

Mitophagy vs. Complex I Inhibitors: Which is Better?

July 21, 2025

Discover how mitophagy and Complex I inhibitors impact aging, inflammation, and tissue repair—and which path may best support healthy mitochondrial function.

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Autophagy and Senescent Cells: Restoring the Immune Cleanup

Menopause and Aging: Study Maps a Sharp Physiological Transition

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

SRSF1 and Aging: A Gene-Splicing Target Shows Promise in Mice

Senolytic Kidney Rejuvenation: Eight Months of Dasatinib + Quercetin

Diet

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

Ferro-Aging: Iron and Lipid Damage May Be Driving Aging at Its Core

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Polyphenols and Longevity, Reviewed!

Latest

Omega Fatty Acids: 3, 6, and 9 Explained

The Body’s Fuel Gauge: How Nutrient Sensing Shapes Human Aging

Do Dogs Help Us Age Better? Here’s What the Latest Science Actually Says.

Blue light, sleep, and aging: what the strongest science actually says

Synthetic Biology vs. Aging in the Quest for Human Longevity

Circadian Rhythms and Longevity: The Science of Aging on Time

Bone Deep: How Your Skeleton Secretly Shapes Your Longevity

What Is Structured Procrastination?

Senolytic Immune Cells Get a Facelift

Mitophagy vs. Complex I Inhibitors: Which is Better?

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Brandon Rodriguez

Emily Wilson

Christopher Martinez

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Autophagy and Senescent Cells: Restoring the Immune Cleanup

Menopause and Aging: Study Maps a Sharp Physiological Transition

PLA2G15 and Kidney Aging: Why Lysosomal Lipid Composition Matters

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