Longevityreview

A luminous network of glowing blue nodes rises like a futuristic constellation against a cosmic horizon, each pillar crowned with a symbol of life’s machinery—DNA strands, chromosomes, mitochondria, and molecular structures—interwoven by radiant strands of light. The connections cascade downward into a dense web, suggesting a living system in motion, where biology is not isolated but intricately linked. Set against a gradient sky that shifts from deep indigo to warm orange, the scene evokes both the precision of advanced science and the quiet vastness of space, portraying aging as a complex, interconnected system rather than a single failing pillar.

Is Aging a Systems Problem? Microbiome, Immunity, and the Limits of Anti-Aging Science

New longevity science points to microbiome–immune–metabolic networks. Here’s what’s real, what’s uncertain, and what you can do now.

March 27, 2026

Health·Science·Technology

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

March 21, 2026

Biotechnology·Diet·Science·Technology

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

March 20, 2026

Biotechnology·Health·Science·Technology

A curated still life of polyphenol-rich foods arranged against a serene turquoise backdrop. A crisp red-striped apple rests in the foreground, while squares of dark chocolate perch on minimalist pale-blue blocks beside hazelnuts, loose green tea leaves, and a handwritten “Polyphenols” label. Behind them, clusters of green grapes, ruby strawberries, a glossy purple onion, and a single white garlic bulb create a vibrant tableau of color and texture, evoking the natural abundance of plant-based compounds that shape human health and longevity.

Polyphenols and Longevity, Reviewed!

Christopher Martinez

A small circle of older friends gathers outdoors beneath a canopy of warm evening light, faces alive with laughter and recognition. Their hands rest gently on each other’s shoulders as if closing an invisible circuit of care. Behind them, the soft blur of trees and sky seems to echo their calm vitality—a quiet visual proof that belonging itself is a form of medicine. The scene radiates the essence of social embeddedness: the way human connection slows the passage of time and nourishes longevity more deeply than any supplement ever could.

The Longevity of “Us”: What Social Embedding Really Does to Human Aging

Brandon Rodriguez

A flat lay of sleep essentials rests against a deep blue background: two silky eye masks embroidered with closed golden lashes, one in midnight blue and the other in soft blush; a vintage mint-green alarm clock frozen at an early hour; scattered white tablets and a teabag suggesting nighttime rituals; delicate white feathers drifting like fragments of dreams; and small yellow stars placed playfully around the scene. The composition evokes the quiet architecture of restful sleep and the circadian cues that guide the body’s nightly restoration.

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

Tyler Kim

Diet

Biotechnology·Diet·Science·Technology

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

March 21, 2026

Longevity science is shifting from NAD+ supplements to precision anti-aging therapies. Here’s what the data actually shows and what comes next.

Biotechnology·Diet·Health·Science·Technology

Polyphenols and Longevity, Reviewed!

December 1, 2025

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

Diet·Health·Lifestyle·Science

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

November 25, 2025

How men and women age differently through the lens of circadian rhythms—exploring sleep, hormones, metabolism, and longevity through the science of our internal clocks.

A sleepless person sits upright in bed with hands gently pressed to their temples, eyes tired and face drawn with exhaustion. Soft cartoon sheep float across a deep blue night sky scattered with tiny stars, suggesting the familiar struggle of counting sheep that offers no relief. The scene conveys the quiet frustration and emotional weight of insomnia, capturing the intimate moment when the mind refuses to rest even as the world around grows still.

Biotechnology·Diet·Health·Lifestyle·Science

The Night Shift of Aging: Why Sleep Changes As We Get Older

November 17, 2025

How insomnia and sleep apnea shape aging, summarizing new evidence on mortality, cognition, frailty, and treatments that can bend the curve.

Latest

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Biotechnology·Diet·Health·Lifestyle·Politics·Science

Celebrating the International Day of Older Persons

October 1, 2025

Your practical guide to longevity and being celebrated one day.

An image of two skeletons shaking hands and conversing in front of a black background. Above their skeleton skulls, a spooky, haunting font with sharp lines and jagged edges reads "The Bones Are Talking... Is Your Lifespan Listening?"

Biotechnology·Health·Science

The Bones Are Talking. Is Your Lifespan Listening?

October 1, 2025

Bones do more than support—they secrete hormones like osteocalcin and Klotho that regulate aging, metabolism, immunity, and longevity.

An image illustrating some of the potential benefits that sirtuins provide. In the image, these include lipid metabolism in adipose tissue, neuroprotection, glucose and lipid homeostasis in the liver, repair and function in the muscle, and regulation of insulin secretion in the pancreas.

Biotechnology·Health·Products & Supplements·Science

Enzymes and Longevity, Reviewed!

September 29, 2025

Discover how aging enzymes—from sirtuins to ELOVL2 and methylation markers—shape longevity and what new research reveals for boosting healthspan.

An image of a questionaire with a single question, asking "Progeria: Do you know about it? There are two boxes for "Yes" and "No" with a pen hovering over the "No" box.

Biotechnology·Health·Science

Progeria, Progerin, and the Playbook of Human Aging

September 25, 2025

Learn about Progeria, what it is, why longevity researchers are interested, and how it impacts aging.

Health·Products & Supplements

Creatine: Enhancing Athletic Prowess and Cognitive Function

September 22, 2025

Creatine monohydrate boosts athletic performance and muscle mass, supports brain health, and is generally safe when taken at recommended doses.

Diet·Health

A Deep Dive into Dietary Fiber and Disease Prevention

September 18, 2025

Dietary fiber helps prevent chronic diseases like heart disease, type 2 diabetes, and chronic kidney disease. Increase fiber with whole grains, fruits, and vegetables.

Diet·Health·Lifestyle

Beyond the Hype: Understanding the Science of the Ketogenic Diet

September 16, 2025

The ketogenic diet promotes weight loss and better focus through low-carb, high-fat eating. Transition can be tough; consult a doctor before starting.

Lifestyle

Aerobic Exercise For Healthy Body and Mind

September 11, 2025

What is Aerobic Exercise? Aerobic exercise, often called ‘cardio,’ is a term referring to activities that raise your heart rate and keep it elevated

Diet

Intermittent Fasting: A Comprehensive Guide to Methods, Benefits, and Personal Experiences

September 8, 2025

What is Intermittent Fasting? Intermittent fasting (IF) is a dietary approach that cycles between periods of fasting, not eating, and eating. Unlike traditional diets

Products & Supplements

Vitamin D Decoded: Essential for Health, from Bones to Immunity

September 4, 2025

What is vitamin D and why do we need it? Vitamin D is an essential nutrient for maintaining optimal health. It is needed for

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Is Aging a Systems Problem? Microbiome, Immunity, and the Limits of Anti-Aging Science

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

Polyphenols and Longevity, Reviewed!

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

Diet

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Polyphenols and Longevity, Reviewed!

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

The Night Shift of Aging: Why Sleep Changes As We Get Older

Latest

Celebrating the International Day of Older Persons

The Bones Are Talking. Is Your Lifespan Listening?

Enzymes and Longevity, Reviewed!

Progeria, Progerin, and the Playbook of Human Aging

Creatine: Enhancing Athletic Prowess and Cognitive Function

A Deep Dive into Dietary Fiber and Disease Prevention

Beyond the Hype: Understanding the Science of the Ketogenic Diet

Aerobic Exercise For Healthy Body and Mind

Intermittent Fasting: A Comprehensive Guide to Methods, Benefits, and Personal Experiences

Vitamin D Decoded: Essential for Health, from Bones to Immunity

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Authors

Brandon Rodriguez

Emily Wilson

Christopher Martinez

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Is Aging a Systems Problem? Microbiome, Immunity, and the Limits of Anti-Aging Science

Longevity Science Is Moving Beyond NAD+—Toward Precision Anti-Aging Therapies

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

Polyphenols and Longevity, Reviewed!

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