Longevityreview

A curated still life of polyphenol-rich foods arranged against a serene turquoise backdrop. A crisp red-striped apple rests in the foreground, while squares of dark chocolate perch on minimalist pale-blue blocks beside hazelnuts, loose green tea leaves, and a handwritten “Polyphenols” label. Behind them, clusters of green grapes, ruby strawberries, a glossy purple onion, and a single white garlic bulb create a vibrant tableau of color and texture, evoking the natural abundance of plant-based compounds that shape human health and longevity.

Polyphenols and Longevity, Reviewed!

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

December 1, 2025

Biotechnology·Diet·Health·Science·Technology

A small circle of older friends gathers outdoors beneath a canopy of warm evening light, faces alive with laughter and recognition. Their hands rest gently on each other’s shoulders as if closing an invisible circuit of care. Behind them, the soft blur of trees and sky seems to echo their calm vitality—a quiet visual proof that belonging itself is a form of medicine. The scene radiates the essence of social embeddedness: the way human connection slows the passage of time and nourishes longevity more deeply than any supplement ever could.

The Longevity of “Us”: What Social Embedding Really Does to Human Aging

November 27, 2025

Health·Lifestyle·Science

A flat lay of sleep essentials rests against a deep blue background: two silky eye masks embroidered with closed golden lashes, one in midnight blue and the other in soft blush; a vintage mint-green alarm clock frozen at an early hour; scattered white tablets and a teabag suggesting nighttime rituals; delicate white feathers drifting like fragments of dreams; and small yellow stars placed playfully around the scene. The composition evokes the quiet architecture of restful sleep and the circadian cues that guide the body’s nightly restoration.

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

November 25, 2025

Diet·Health·Lifestyle·Science

A bright red balloon ruptures midair, frozen in the instant its membrane gives way, sending a crystalline explosion of water outward against a clear blue sky. Droplets scatter in every direction like fractured glass, capturing the drama of a boundary pushed past its limit and the sudden release of what was once contained.

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

Sarah Smith

A sleepless person sits upright in bed with hands gently pressed to their temples, eyes tired and face drawn with exhaustion. Soft cartoon sheep float across a deep blue night sky scattered with tiny stars, suggesting the familiar struggle of counting sheep that offers no relief. The scene conveys the quiet frustration and emotional weight of insomnia, capturing the intimate moment when the mind refuses to rest even as the world around grows still.

The Night Shift of Aging: Why Sleep Changes As We Get Older

Ryan Nguyen

An older man with silver hair exercises outdoors, wearing blue headphones and lifting matching blue dumbbells with focused determination. He stands in a lush green park, his posture strong and steady, embodying resilience, strength, and the ongoing capacity to build muscle and vitality at any age.

Can you add muscle after 50? What the latest research really says

Michael Lopez

Diet

Biotechnology·Diet·Health·Science·Technology

Polyphenols and Longevity, Reviewed!

December 1, 2025

Polyphenols reshape how we age, from senescent cells to brain health. Here’s what the latest science really says about food, supplements, and longevity.

Diet·Health·Lifestyle·Science

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

November 25, 2025

How men and women age differently through the lens of circadian rhythms—exploring sleep, hormones, metabolism, and longevity through the science of our internal clocks.

Biotechnology·Diet·Health·Lifestyle·Science

The Night Shift of Aging: Why Sleep Changes As We Get Older

November 17, 2025

How insomnia and sleep apnea shape aging, summarizing new evidence on mortality, cognition, frailty, and treatments that can bend the curve.

Diet·Health·Lifestyle·Products & Supplements·Science

Can you add muscle after 50? What the latest research really says

November 13, 2025

Yes, you can build real muscle after 50. Train smart, eat enough protein, and target power and quality to boost strength, function, and healthy

Latest

Illustration of a human facing a humanoid robot, symbolizing the convergence of biotechnology and engineering in tissue regeneration and organ replacement. The image features gears inside the robot's head, digital data elements, and biological motifs, representing themes of artificial tissue, personalized medicine, and the future of regenerative therapies.

Biotechnology·Health·Politics·Science·Technology

The Future of Tissue Engineering: Regeneration vs. Replacement

April 10, 2025

The future of tissue engineering: stem cells, bioprinting, rejuvenation, and how biotech is transforming regeneration and organ replacement.

A chef holds a raw steak shaped like a heart on a wooden cutting board, surrounded by other cuts of meat in a butcher-style setting.

Biotechnology·Health·Science

Rejuvenating the Aging Heart with Fat?

April 7, 2025

Can fat-derived factors reverse heart aging? Scientists say yes—and the implications for aging and longevity are just getting started.

A fit woman wearing high-waisted jeans and a crop top stands in a modern kitchen, partially putting on a white button-down shirt. Her toned midsection is visible, symbolizing the weight loss and metabolic health benefits often associated with Ozempic (semaglutide) as discussed in the context of anti-aging and longevity therapies.

Biotechnology·Diet·Health·Lifestyle·Politics·Products & Supplements·Science·Technology

Ozempic: The Unexpected Ally in the Quest for Longevity

April 4, 2025

Ozempic already treats more than diabetes—but it could redefine aging by targeting inflammation and metabolism itself.

A smiling young woman recovering from cancer treatment raises her arms in a victorious pose, symbolizing strength and resilience. The image captures a hopeful outlook for patients benefiting from new cancer therapies like dual PROTAC degraders, which not only fight tumors but may also promote healthy aging by targeting senescent cells.

Biotechnology·Health·Products & Supplements·Science

New Cancer Drug Could Boost Longevity

April 1, 2025

New cancer therapy targets BCL-xL/BCL-2 to fight tumors and clear senescent cells—paving the way for safer, longer-lasting anti-aging treatments.

A collection of white and blue capsules arranged on a white background, with some blue capsules forming the letters "AI." The image represents the intersection of artificial intelligence and drug discovery, reflecting advancements in AI-driven pharmaceutical research, including the development of senomorphic therapeutics like TNIK inhibitors.

Biotechnology·Science·Technology

New Senomorphic Strategy for Age-Related Diseases: TNIK Inhibition

March 28, 2025

TNIK inhibition with INS018_055 modulates senescence, reduces inflammation, and advances AI-driven longevity therapeutics.

Abstract blue line art illustration of diverse gut microbiota, including rod-shaped, spherical, and spiral bacterial forms, representing the complexity and richness of the human gut microbiome. This visual metaphorically conveys the microbiome's integral role in regulating aging, cognition, immunity, and overall longevity.

Biotechnology·Diet·Health·Science

Microbiome and Longevity Reviewed! Insights from Long-Lived Humans

March 26, 2025

A New Kind of Organ In the landscape of human biology, no organ has generated as much recent fascination as the one not even

A surreal Martian-like desert landscape under a star-filled sky, with a vibrant Milky Way galaxy stretching across the horizon. A shooting star streaks across the deep twilight gradient, blending from blue to pink to orange. Rugged red rock formations and scattered desert vegetation dot the barren terrain, evoking themes of space colonization, cognitive evolution, and the search for intelligent life beyond Earth. Ideal visual for the “Cognitive Ark” and longevity science in the Dumbpocalypse survival guide.

Biotechnology·Diet·Health·Lifestyle·Politics·Products & Supplements·Science·Technology

The Longevity Field Guide to Surviving the Dumbpocalypse

March 20, 2025

Earth IQs are crashing, but Mars is rising. Escape the Dumbpocalypse with this survival guide on longevity science, neurotech, and cognitive resilience.

Young woman standing peacefully among blooming white lilac flowers in springtime, symbolizing seasonal renewal, natural rejuvenation, and longevity-enhancing environmental exposure.

Health·Lifestyle·Science

Spring Time Unlocks Longevity Pathways

March 19, 2025

Spring time activates immune, circadian, and genetic pathways that enhance healthspan and promote longevity. Seasonal longevity science is a thing, and it could inform

Close-up of a syringe releasing a droplet of fluid onto human skin, symbolizing regenerative medicine and stem cell therapy. The image represents emerging biomedical interventions aiming to restore stem cell function and reverse signs of aging. Would you like a version with more emphasis on specific concepts like epigenetic reprogramming, extracellular vesicles, or clinical translation?

Biotechnology·Health·Science

Stem Cells Reviewed! Regenerative Capacity Beyond Imagination

March 14, 2025

As stem cells lose function with age, scientists are developing targeted rejuvenation therapies to restore regenerative capacity and slow biological aging.

Comparison photomicrograph of bone marrow under a microscope, illustrating stem cell composition and aging effects. The left image shows healthy, youthful bone marrow with abundant hematopoietic stem cells, while the right image depicts aged bone marrow with diminished cellular density and increased signs of stem cell exhaustion. This visual represents the biological decline in regenerative capacity central to aging and longevity research.

Biotechnology·Science

Stem Cell Exhaustion Reviewed! Latest Insights for Longevity.

March 10, 2025

Stem cell exhaustion drives aging by impairing tissue repair. Explore the causes, consequences, and cutting-edge strategies to rejuvenate aging stem cells.

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Polyphenols and Longevity, Reviewed!

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

The Night Shift of Aging: Why Sleep Changes As We Get Older

Can you add muscle after 50? What the latest research really says

Diet

Polyphenols and Longevity, Reviewed!

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

The Night Shift of Aging: Why Sleep Changes As We Get Older

Can you add muscle after 50? What the latest research really says

Latest

The Future of Tissue Engineering: Regeneration vs. Replacement

Rejuvenating the Aging Heart with Fat?

Ozempic: The Unexpected Ally in the Quest for Longevity

New Cancer Drug Could Boost Longevity

New Senomorphic Strategy for Age-Related Diseases: TNIK Inhibition

Microbiome and Longevity Reviewed! Insights from Long-Lived Humans

The Longevity Field Guide to Surviving the Dumbpocalypse

Spring Time Unlocks Longevity Pathways

Stem Cells Reviewed! Regenerative Capacity Beyond Imagination

Stem Cell Exhaustion Reviewed! Latest Insights for Longevity.

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Emily Wilson

Brandon Rodriguez

Christopher Martinez

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Polyphenols and Longevity, Reviewed!

Sex-Specific Differences in Circadian Rhythms and Aging, Reviewed!

Lysosomal Permeability, Reviewed! New Contender in The Hallmarks of Aging

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