Longevityreview

A contemplative older woman sits at her desk, laptop open, glasses in hand, as an hourglass steadily drains on the table before her—a quiet metaphor for time, aging, and the rhythms that govern life.

Chronotherapy, aging, and the body’s master timetable

Chronotherapy for healthy aging: how timing sleep, light, meals, and meds can help—what’s proven, what’s hype—using current human evidence.

October 14, 2025

Health·Lifestyle·Science·Technology

A double helix of DNA unfurls across the canvas in a splash of vivid color, each twisting strand painted in gradients of orange, green, blue, and violet. The structure appears alive, with pigments bursting outward like fragments of energy scattering into the air, evoking both the beauty and fragility of life’s code. The edges fade into soft washes of gray and teal, framing the central spiral as if suspended between order and chaos.

Genomic Instability: When the Instruction Manual Frays

October 8, 2025

Biotechnology·Health·Science

Close-up of an elderly hand clasped over the other, its weathered skin carrying a constellation of dark age spots across the knuckles and wrist. The fine lines and mottled pigment tell a quiet story of time, sun, and cellular change, a living canvas where lipofuscin’s presence makes itself visible as speckled marks of aging.

Lipofuscin and Aging, Reviewed!

October 6, 2025

Biotechnology·Products & Supplements·Science·Technology

Four women stand shoulder to shoulder beneath a wide blue sky, laughter softening their faces. Their arms rest easily around each other, denim and bright colors mingling, the warmth of friendship and resilience shining through their smiles. The image evokes the vitality and joy of healthy aging.

Celebrating the International Day of Older Persons

Emily Wilson

An image of two skeletons shaking hands and conversing in front of a black background. Above their skeleton skulls, a spooky, haunting font with sharp lines and jagged edges reads "The Bones Are Talking... Is Your Lifespan Listening?"

The Bones Are Talking. Is Your Lifespan Listening?

Tyler Kim

Seragon’s SRN-901: Breakthrough Aging Intervention Drug Achieves Dramatic Lifespan Extension in Preclinical Study

Michael Lopez

Diet

Biotechnology·Diet·Health·Lifestyle·Politics·Science

Celebrating the International Day of Older Persons

October 1, 2025

Your practical guide to longevity and being celebrated one day.

Diet·Health

A Deep Dive into Dietary Fiber and Disease Prevention

September 18, 2025

Dietary fiber helps prevent chronic diseases like heart disease, type 2 diabetes, and chronic kidney disease. Increase fiber with whole grains, fruits, and vegetables.

Diet·Health·Lifestyle

Beyond the Hype: Understanding the Science of the Ketogenic Diet

September 16, 2025

The ketogenic diet promotes weight loss and better focus through low-carb, high-fat eating. Transition can be tough; consult a doctor before starting.

Diet

Intermittent Fasting: A Comprehensive Guide to Methods, Benefits, and Personal Experiences

September 8, 2025

What is Intermittent Fasting? Intermittent fasting (IF) is a dietary approach that cycles between periods of fasting, not eating, and eating. Unlike traditional diets

Latest

A collection of white and blue capsules arranged on a white background, with some blue capsules forming the letters "AI." The image represents the intersection of artificial intelligence and drug discovery, reflecting advancements in AI-driven pharmaceutical research, including the development of senomorphic therapeutics like TNIK inhibitors.

Biotechnology·Science·Technology

New Senomorphic Strategy for Age-Related Diseases: TNIK Inhibition

March 28, 2025

TNIK inhibition with INS018_055 modulates senescence, reduces inflammation, and advances AI-driven longevity therapeutics.

Abstract blue line art illustration of diverse gut microbiota, including rod-shaped, spherical, and spiral bacterial forms, representing the complexity and richness of the human gut microbiome. This visual metaphorically conveys the microbiome's integral role in regulating aging, cognition, immunity, and overall longevity.

Biotechnology·Diet·Health·Science

Microbiome and Longevity Reviewed! Insights from Long-Lived Humans

March 26, 2025

A New Kind of Organ In the landscape of human biology, no organ has generated as much recent fascination as the one not even

A surreal Martian-like desert landscape under a star-filled sky, with a vibrant Milky Way galaxy stretching across the horizon. A shooting star streaks across the deep twilight gradient, blending from blue to pink to orange. Rugged red rock formations and scattered desert vegetation dot the barren terrain, evoking themes of space colonization, cognitive evolution, and the search for intelligent life beyond Earth. Ideal visual for the “Cognitive Ark” and longevity science in the Dumbpocalypse survival guide.

Biotechnology·Diet·Health·Lifestyle·Politics·Products & Supplements·Science·Technology

The Longevity Field Guide to Surviving the Dumbpocalypse

March 20, 2025

Earth IQs are crashing, but Mars is rising. Escape the Dumbpocalypse with this survival guide on longevity science, neurotech, and cognitive resilience.

Young woman standing peacefully among blooming white lilac flowers in springtime, symbolizing seasonal renewal, natural rejuvenation, and longevity-enhancing environmental exposure.

Health·Lifestyle·Science

Spring Time Unlocks Longevity Pathways

March 19, 2025

Spring time activates immune, circadian, and genetic pathways that enhance healthspan and promote longevity. Seasonal longevity science is a thing, and it could inform

Close-up of a syringe releasing a droplet of fluid onto human skin, symbolizing regenerative medicine and stem cell therapy. The image represents emerging biomedical interventions aiming to restore stem cell function and reverse signs of aging. Would you like a version with more emphasis on specific concepts like epigenetic reprogramming, extracellular vesicles, or clinical translation?

Biotechnology·Health·Science

Stem Cells Reviewed! Regenerative Capacity Beyond Imagination

March 14, 2025

As stem cells lose function with age, scientists are developing targeted rejuvenation therapies to restore regenerative capacity and slow biological aging.

Comparison photomicrograph of bone marrow under a microscope, illustrating stem cell composition and aging effects. The left image shows healthy, youthful bone marrow with abundant hematopoietic stem cells, while the right image depicts aged bone marrow with diminished cellular density and increased signs of stem cell exhaustion. This visual represents the biological decline in regenerative capacity central to aging and longevity research.

Biotechnology·Science

Stem Cell Exhaustion Reviewed! Latest Insights for Longevity.

March 10, 2025

Stem cell exhaustion drives aging by impairing tissue repair. Explore the causes, consequences, and cutting-edge strategies to rejuvenate aging stem cells.